UNODC World Drug Report 2025: Global instability compounding social, economic and security costs of the world drug problem

By: Michael Mike

A new era of global instability has intensified challenges in addressing the world drug problem, empowering organized crime groups and pushing drug use to historically high levels, says the UN Office on Drugs and Crime (UNODC) in the World Drug Report 2025 launched on Thursday.

“This edition of the World Drug Report shows that organized drug trafficking groups continue to adapt, exploit global crises, and target vulnerable populations,” said the Executive Director of UNODC, Ghada Waly,

She said: “We must invest in prevention and address the root causes of the drug trade at every point of the illicit supply chain. And we must strengthen responses, by leveraging technology, strengthening cross-border cooperation, providing alternative livelihoods, and taking judicial action that targets key actors driving these networks. Through a comprehensive, coordinated approach, we can dismantle criminal organizations, bolster global security, and protect our communities.”

According to the report, 316 million people used a drug (excluding alcohol and tobacco) in 2023, or six per cent of the population aged between 15 and 64, compared to 5.2 per cent of the population in 2013. With 244 million users, cannabis remains the most widely used drug, followed by opioids (61 million), amphetamines (30.7 million), cocaine (25 million) and “ecstasy” (21 million).

Within Nigeria, cannabis remains the most widely used illicit substance, and worryingly, one in three users report needing treatment or counselling—underscoring a significant gap in health services and support.

New groups of vulnerable people fleeing hardship, instability and conflict could cause these numbers to increase further, the report warned. Globally, as indicated by limited sex-disaggregated data, 5.5 per cent of women with drug use disorders were in treatment in 2023, as compared with 13.6 per cent of men with such disorders.

Production, seizures, and use of cocaine all hit new highs in 2023, making cocaine the world’s fastest-growing illicit drug market. Illegal production skyrocketed to 3,708 tons, nearly 34 per cent more than in 2022. Global cocaine seizures reached a record high at 2,275– a 68 per cent rise over 2019-2023. Use of cocaine, meanwhile, has grown from 17 million users in 2013 to 25 million users in 2023.

Cocaine traffickers are breaking into new markets across Asia and Africa, the report notes. The abuse of pharmaceutical opioids, especially tramadol, has also reached alarming levels, with the majority of global tramadol seizures taking place in Africa.

Due to factors like low operational costs and reduced risks of detection, the synthetic drug market continues to expand globally, dominated by Amphetamine-type stimulants (ATS) like methamphetamine and amphetamine (including “captagon”).

Seizures of ATS reached a record high in 2023 and accounted for almost half of all global seizures of synthetic drugs, followed by synthetic opioids, including fentanyl.

The report stated that though estimates vary, the illicit drug trade generates hundreds of billions of dollars per year. Criminal groups innovate constantly, through boosting production, finding new ways to chemically conceal their drugs, and using technology to conceal communications and increase distribution.

It also stated that though resilient, organized criminal networks can be disrupted – but a deeper understanding of the aims and structures of drug trafficking groups is required. Mapping criminal groups can highlight their vulnerabilities, key actors, enablers, and pinpoint possible areas for intervention. Law enforcement agencies could also consider investing in technology and skills training that matches the sophistication of tools used in the drug supply chain.

It explained that evidence suggests that integrating drug use disorder treatment and care into existing healthcare systems improves the quality, effectiveness and efficiency of that treatment and care. Such integration requires, among other measures, that a sufficient number of health professionals be trained and equipped with the necessary tools, which is not a simple task, particularly in systems already hampered by a struggle for resources.

With a national drug use prevalence of 14.4%, nearly three times the global average, and with over 3 million people in Nigeria suffering from drug use disorders, the toll of illicit drug use is significant and growing. Particularly alarming is the 9.2% HIV prevalence among people who inject drugs, and the still limited access to evidence-based treatment services.

Representative, UNODC Country office, Nigeria, Cheikh Toure, noted that: “This is not just a health crisis — it is a development, security, and peacebuilding concern.”

He said in Africa, for example, only 3.4 per cent of the estimated number of individuals with drug use disorders receive treatment. To strengthen evidence-based treatment, Governments must prioritize cost-effective interventions based on public health principles.

UNODC World Drug Report 2025: Global instability compounding social, economic and security costs of the world drug problem